| Game Name | System |
|---|
| Soreyuke!! Kid (Japan) | GB |
| Soukoban (Japan) | GB |
| Soukoban 2 (Japan) | GB |
| Space Invaders (Europe) | GB |
| Space Invaders (Japan) | GB |
| Space Invaders (USA) | GB |
| Spanky's Quest (Europe) | GB |
| Spanky's Quest (USA) | GB |
| Spartan X (Japan) | GB |
| Speedball 2 - Brutal Deluxe (USA, Europe) | GB |
| Speedy Gonzales (USA, Europe) | GB |
| Spider-Man and the X-Men in Arcade's Revenge (USA, Europe) | GB |
| Spirit of F-1, The (Europe) | GB |
| Spiritual Warfare (USA) (Unl) | GB |
| Spirou (Europe) (En,Fr,De,Es) | GB |
| Spirou (Europe) (En,Fr,De,Es) (Beta) | GB |
| Splitz (Europe) | GB |
| Splitz - Nigaoe 15 Game (Japan) | GB |
| Sports Collection (Japan) | GB |
| Sports Illustrated - Football & Baseball (USA) | GB |
| Sports Illustrated - Golf Classic (USA) | GB |
| Sports Illustrated for Kids - The Ultimate Triple Dare! (USA) | GB |
| Spot (Europe) | GB |
| Spot (Japan) | GB |
| Spot (USA) | GB |
| Spot - The Cool Adventure (Japan) | GB |
| Spot - The Cool Adventure (USA) | GB |
| Spud's Adventure (USA) | GB |
| Spy vs Spy - Operation Boobytrap (Europe) | GB |
| Spy vs Spy - Operation Boobytrap (USA) | GB |
| Square Deal (USA) | GB |
| Star Hawk (Europe) | GB |
| Star Sweep (Japan) | GB |
| Star Trek - 25th Anniversary (USA, Europe) | GB |
| Star Trek - The Next Generation (Germany) | GB |
| Star Trek - The Next Generation (Spain) | GB |
| Star Trek - The Next Generation (USA, Europe) | GB |
| Star Trek Generations - Beyond the Nexus (Europe) | GB |
| Star Trek Generations - Beyond the Nexus (USA) | GB |
| Star Wars (Europe) | GB |
| Star Wars (USA) | GB |
| Star Wars (USA, Europe) (Rev A) | GB |
| Star Wars - The Empire Strikes Back (Europe) | GB |
| Star Wars - The Empire Strikes Back (USA) | GB |
| Stargate (USA, Europe) | GB |
| Stop That Roach! (USA) | GB |
| Street Fighter II (Japan) | GB |
| Street Fighter II (USA, Europe) (Rev A) | GB |
| Street Racer (Japan) | GB |
| Street Racer (USA, Europe) | GB |
| Sumo Fighter (USA) | GB |
| Sumou Fighter - Toukaidou Basho (Japan) | GB |
| Sunsoft Grand Prix (Europe) | GB |
| Super B-Daman - Fighting Phoenix (Japan) | GB |
| Super Battletank (Europe) | GB |
| Super Battletank - War in the Gulf (USA) | GB |
| Super Bikkuriman - Densetsu no Sekiban (Japan) | GB |
| Super Bikkuriman - Densetsu no Sekiban (Japan) [En by PentarouZero v1.0] (~Super Bikkuriman - The Legendary Tablet) | GB |
| Super Black Bass (USA) | GB |
| Super Black Bass Pocket (Japan) | GB |
| Super Black Bass Pocket 2 (Japan) | GB |
| Super Bombliss (Japan) | GB |
| Super Chase H.Q. (USA, Europe) | GB |
| Super Chinese Fighter GB (Japan) | GB |
| Super Chinese Land (Japan) | GB |
| Super Chinese Land 1.2.3' (Japan) | GB |
| Super Chinese Land 2 (Japan) | GB |
| Super Chinese Land 3 (Japan) | GB |
| Super Hunchback (Europe) | GB |
| Super Hunchback (Japan) | GB |
| Super Hunchback (USA) | GB |
| Super James Pond (Europe) | GB |
| Super Kick Off (Europe) (En,Fr,De,It,Nl) | GB |
| Super Momotarou Dentetsu (Japan) | GB |
| Super Momotarou Dentetsu II (Japan) | GB |
| Super Off Road (USA) | GB |
| Super Pachinko Taisen (Japan) | GB |
| Super R.C. Pro-Am (USA, Europe) | GB |
| Super Robot Taisen (Japan) | GB |
| Super Robot Taisen (Japan) [En by Aeon Genesis v1.0] (~Super Robot Wars) | GB |
| Super Scrabble (USA) | GB |
| Super Snakey (Japan) | GB |
| Super Star Wars - Return of the Jedi (USA, Europe) | GB |
| Super Street Basketball (Japan) | GB |
| Super Street Basketball 2 (Japan) | GB |
| Superman (USA, Europe) | GB |
| Suzuki Aguri no F-1 Super Driving (Japan) | GB |
| Swamp Thing (USA, Europe) | GB |
| Sword of Hope II, The (USA) | GB |
| Sword of Hope, The (Germany) | GB |
| Sword of Hope, The (Spain) | GB |
| Sword of Hope, The (Sweden) | GB |
| Sword of Hope, The (USA) | GB |
| T2 - The Arcade Game (Japan) | GB |
| T2 - The Arcade Game (USA, Europe) | GB |
| TV Champion (Japan) | GB |
| Taikyoku Renju (Japan) (En,Ja) | GB |
| Tail 'Gator (USA, Europe) | GB |
| Taito Chase H.Q. (Japan) | GB |
| Taito Variety Pack (Japan) | GB |
